Research

Research

FYZICAL Therapy & Balance Center Phoenix Midtown engages in extensive medical research. Our staff has published over 80 scientific research papers in muscle and connective tissue biology, making us one of the most extensively published rehabilitation groups in the country. For our patients this means that you obtain high quality therapy from clinicians who are truly leaders in their field. 

The following is a list of some of our research papers:

1: Li H, Korcari A, Ciufo D, Mendias CL, Rodeo SA, Buckley MR, Loiselle AE, Pitt
GS, Cao C. Increased Ca 2+ signaling through Ca V 1.2
induces tendon hypertrophy with increased collagen fibrillogenesis and
biomechanical properties. bioRxiv [Preprint]. 2023 Jan 24:2023.01.24.525119.
doi: 10.1101/2023.01.24.525119. PMID: 36747837; PMCID: PMC9900778.

2: Patel SH, Mendias CL, Carroll CC. Descriptive transcriptome analysis of
tendon derived fibroblasts following in-vitro exposure to advanced glycation end
products. PLoS One. 2022 Jul 26;17(7):e0271770. doi:
10.1371/journal.pone.0271770. PMID: 35881579; PMCID: PMC9321369.

3: LeBrun DG, Konnaris MA, Ghahramani GC, Premkumar A, DeFrancesco CJ, Gruskay
JA, Dvorzhinskiy A, Sandhu MS, Goldwyn EM, Mendias CL, Ricci WM. Increased
Comorbidity Burden Among Hip Fracture Patients During the COVID-19 Pandemic in
New York City. Geriatr Orthop Surg Rehabil. 2021 Sep 11;12:21514593211040611.
doi: 10.1177/21514593211040611. PMID: 34522445; PMCID: PMC8436002.

4: Olesen JL, Hansen M, Turtumoygard IF, Hoffner R, Schjerling P, Christensen J,
Mendias CL, Magnusson PS, Kjaer M. No Treatment Benefits of Local Administration
of Insulin-like Growth Factor-1 in Addition to Heavy Slow Resistance Training in
Tendinopathic Human Patellar Tendons: A Randomized, Double-Blind, Placebo-
Controlled Trial With 1-Year Follow-up. Am J Sports Med. 2021
Jul;49(9):2361-2370. doi: 10.1177/03635465211021056. Epub 2021 Jun 17. PMID:
34138667.

5: Jeffery NS, Sarver DC, Mendias CL. Ontogenetic and in silico models of
spatial-packing in the hypermuscular mouse skull. J Anat. 2021
Jun;238(6):1284-1295. doi: 10.1111/joa.13393. Epub 2021 Jan 13. PMID: 33438210;
PMCID: PMC8128773.

6: De Micheli AJ, Swanson JB, Disser NP, Martinez LM, Walker NR, Oliver DJ,
Cosgrove BD, Mendias CL. Single-cell transcriptomic analysis identifies
extensive heterogeneity in the cellular composition of mouse Achilles tendons.
Am J Physiol Cell Physiol. 2020 Nov 1;319(5):C885-C894. doi:
10.1152/ajpcell.00372.2020. Epub 2020 Sep 2. PMID: 32877217; PMCID: PMC7701267.

7: Disser NP, De Micheli AJ, Schonk MM, Konnaris MA, Piacentini AN, Edon DL,
Toresdahl BG, Rodeo SA, Casey EK, Mendias CL. Musculoskeletal Consequences of
COVID-19. J Bone Joint Surg Am. 2020 Jul 15;102(14):1197-1204. doi:
10.2106/JBJS.20.00847. PMID: 32675661; PMCID: PMC7508274.

8: Van Pelt DW, Kharaz YA, Sarver DC, Eckhardt LR, Dzierzawski JT, Disser NP,
Piacentini AN, Comerford E, McDonagh B, Mendias CL. Multiomics analysis of the
mdx/mTR mouse model of Duchenne muscular dystrophy. Connect Tissue Res. 2021
Jan;62(1):24-39. doi: 10.1080/03008207.2020.1791103. Epub 2020 Jul 15. PMID:
32664808.

9: Gruskay JA, Dvorzhinskiy A, Konnaris MA, LeBrun DG, Ghahramani GC, Premkumar
A, DeFrancesco CJ, Mendias CL, Ricci WM. Universal Testing for COVID-19 in
Essential Orthopaedic Surgery Reveals a High Percentage of Asymptomatic
Infections. J Bone Joint Surg Am. 2020 Aug 19;102(16):1379-1388. doi:
10.2106/JBJS.20.01053. PMID: 32516279.

10: LeBrun DG, Konnaris MA, Ghahramani GC, Premkumar A, DeFrancesco CJ, Gruskay
JA, Dvorzhinskiy A, Sandhu MS, Goldwyn EM, Mendias CL, Ricci WM. Hip Fracture
Outcomes During the COVID-19 Pandemic: Early Results From New York. J Orthop
Trauma. 2020 Aug;34(8):403-410. doi: 10.1097/BOT.0000000000001849. PMID:
32482977; PMCID: PMC7302077.

11: Gumucio JP, Schonk MM, Kharaz YA, Comerford E, Mendias CL. Scleraxis is
required for the growth of adult tendons in response to mechanical loading. JCI
Insight. 2020 Jul 9;5(13):e138295. doi: 10.1172/jci.insight.138295. PMID:
32463804; PMCID: PMC7406294.

12: Mendias CL, Enselman ERS, Olszewski AM, Gumucio JP, Edon DL, Konnaris MA,
Carpenter JE, Awan TM, Jacobson JA, Gagnier JJ, Barkan AL, Bedi A. The Use of
Recombinant Human Growth Hormone to Protect Against Muscle Weakness in Patients
Undergoing Anterior Cruciate Ligament Reconstruction: A Pilot, Randomized
Placebo-Controlled Trial. Am J Sports Med. 2020 Jul;48(8):1916-1928. doi:
10.1177/0363546520920591. Epub 2020 May 26. PMID: 32452208; PMCID: PMC7351248.

13: Curran MT, Bedi A, Mendias CL, Wojtys EM, Kujawa MV, Palmieri-Smith RM.
Blood Flow Restriction Training Applied With High-Intensity Exercise Does Not
Improve Quadriceps Muscle Function After Anterior Cruciate Ligament
Reconstruction: A Randomized Controlled Trial. Am J Sports Med. 2020
Mar;48(4):825-837. doi: 10.1177/0363546520904008. PMID: 32167837.

14: Disser NP, Ghahramani GC, Swanson JB, Wada S, Chao ML, Rodeo SA, Oliver DJ,
Mendias CL. Widespread diversity in the transcriptomes of functionally divergent
limb tendons. J Physiol. 2020 Apr;598(8):1537-1550. doi: 10.1113/JP279646. Epub
2020 Mar 30. PMID: 32083717; PMCID: PMC7351251.

15: Noah AC, Li TM, Martinez LM, Wada S, Swanson JB, Disser NP, Sugg KB, Rodeo
SA, Lu TT, Mendias CL. Adaptive and innate immune cell responses in tendons and
lymph nodes after tendon injury and repair. J Appl Physiol (1985). 2020 Mar
1;128(3):473-482. doi: 10.1152/japplphysiol.00682.2019. Epub 2020 Jan 16. PMID:
31944888; PMCID: PMC7099435.

16: Sarver DC, Sugg KB, Talarek JR, Swanson JB, Oliver DJ, Hinken AC, Kramer HF,
Mendias CL. Prostaglandin D2 signaling is not involved in the
recovery of rat hind limb tendons from injury. Physiol Rep. 2019
Nov;7(22):e14289. doi: 10.14814/phy2.14289. PMID: 31782241; PMCID: PMC6882956.

17: Talarek JR, Piacentini AN, Konja AC, Wada S, Swanson JB, Nussenzweig SC,
Dines JS, Rodeo SA, Mendias CL. The MRL/MpJ Mouse Strain Is Not Protected From
Muscle Atrophy and Weakness After Rotator Cuff Tear. J Orthop Res. 2020
Apr;38(4):811-822. doi: 10.1002/jor.24516. Epub 2019 Nov 17. PMID: 31696955;
PMCID: PMC7071998.

18: Disser NP, Sugg KB, Talarek JR, Sarver DC, Rourke BJ, Mendias CL. Insulin-
like growth factor 1 signaling in tenocytes is required for adult tendon growth.
FASEB J. 2019 Nov;33(11):12680-12695. doi: 10.1096/fj.201901503R. Epub 2019 Sep
16. PMID: 31536390; PMCID: PMC6902672.

19: Mendias CL, Bedi A. RE: Talks BJ, Fernquest S, Palmer A, et al. 2019. No
Evidence of Systemic Inflammation in Symptomatic Patients With Femoroacetabular
Impingement. J Orthop Res. 2019 Dec;37(12):2621-2622. doi: 10.1002/jor.24427.
Epub 2019 Aug 22. PMID: 31343771.

20: Gok E, Alghanem F, Lim E, Sarver D, Eckhardt L, Christensen S, Hoenerhoff M,
Mendias C, Ozer K. Single Muscle Fibre Contractility Testing in Rats to Quantify
Ischaemic Muscle Damage During Reperfusion Injury. Eur J Vasc Endovasc Surg.
2019 Aug;58(2):249-256. doi: 10.1016/j.ejvs.2019.01.009. Epub 2019 Jun 12. PMID:
31202581.

21: Gumucio JP, Qasawa AH, Ferrara PJ, Malik AN, Funai K, McDonagh B, Mendias
CL. Reduced mitochondrial lipid oxidation leads to fat accumulation in
myosteatosis. FASEB J. 2019 Jul;33(7):7863-7881. doi: 10.1096/fj.201802457RR.
Epub 2019 Apr 2. PMID: 30939247; PMCID: PMC6593892.

22: Pataky MW, Yu CS, Nie Y, Arias EB, Singh M, Mendias CL, Ploutz-Snyder RJ,
Cartee GD. Skeletal muscle fiber type-selective effects of acute exercise on
insulin-stimulated glucose uptake in insulin-resistant, high-fat-fed rats. Am J
Physiol Endocrinol Metab. 2019 May 1;316(5):E695-E706. doi:
10.1152/ajpendo.00482.2018. Epub 2019 Feb 12. PMID: 30753114; PMCID: PMC6580167.

23: Schubert MF, Noah AC, Bedi A, Gumucio JP, Mendias CL. Reduced Myogenic and
Increased Adipogenic Differentiation Capacity of Rotator Cuff Muscle Stem Cells.
J Bone Joint Surg Am. 2019 Feb 6;101(3):228-238. doi: 10.2106/JBJS.18.00509.
PMID: 30730482; PMCID: PMC6791507.

24: Ahtiainen JP, Lensu S, Ruotsalainen I, Schumann M, Ihalainen JK, Fachada V,
Mendias CL, Brook MS, Smith K, Atherton PJ, Koch LG, Britton SL, Kainulainen H.
Physiological adaptations to resistance training in rats selectively bred for
low and high response to aerobic exercise training. Exp Physiol. 2018
Nov;103(11):1513-1523. doi: 10.1113/EP087144. Epub 2018 Oct 9. PMID: 30184287;
PMCID: PMC6519084.

25: Syverud BC, Gumucio JP, Rodriguez BL, Wroblewski OM, Florida SE, Mendias CL,
Larkin LM. A Transgenic tdTomato Rat for Cell Migration and Tissue Engineering
Applications. Tissue Eng Part C Methods. 2018 May;24(5):263-271. doi:
10.1089/ten.TEC.2017.0406. Epub 2018 Apr 10. PMID: 29490563; PMCID: PMC5946766.

26: Gumucio JP, Sugg KB, Enselman ERS, Konja AC, Eckhardt LR, Bedi A, Mendias
CL. Anterior cruciate ligament tear induces a sustained loss of muscle fiber
force production. Muscle Nerve. 2018 Jan 18:10.1002/mus.26075. doi:
10.1002/mus.26075. Epub ahead of print. PMID: 29346717; PMCID: PMC6051936.

27: Sugg KB, Markworth JF, Disser NP, Rizzi AM, Talarek JR, Sarver DC, Brooks
SV, Mendias CL. Postnatal tendon growth and remodeling require platelet-derived
growth factor receptor signaling. Am J Physiol Cell Physiol. 2018 Apr
1;314(4):C389-C403. doi: 10.1152/ajpcell.00258.2017. Epub 2017 Dec 13. PMID:
29341790; PMCID: PMC5966786.

28: Mead MP, Gumucio JP, Awan TM, Mendias CL, Sugg KB. Pathogenesis and
Management of Tendinopathies in Sports Medicine. Transl Sports Med. 2018
Jan;1(1):5-13. doi: 10.1002/tsm2.6. Epub 2017 Dec 19. PMID: 31131372; PMCID:
PMC6530902.

29: Lee S, Gumucio J, Mendias C, Bedi A. What is the role of systemic conditions
and options for manipulation of bone formation and bone resorption in rotator
cuff tendon healing and repair? Tech Shoulder Elb Surg. 2017 Sep;18(3):113-120.
doi: 10.1097/BTE.0000000000000121. PMID: 28966557; PMCID: PMC5615853.

30: Novakova SS, Mahalingam VD, Florida SE, Mendias CL, Allen A, Arruda EM, Bedi
A, Larkin LM. Tissue-engineered tendon constructs for rotator cuff repair in
sheep. J Orthop Res. 2018 Jan;36(1):289-299. doi: 10.1002/jor.23642. Epub 2017
Jul 31. PMID: 28657154.

31: Mendias CL. Fibroblasts take the centre stage in human skeletal muscle
regeneration. J Physiol. 2017 Aug 1;595(15):5005. doi: 10.1113/JP274403. Epub
2017 Jun 27. PMID: 28585689; PMCID: PMC5538237.

32: Sarver DC, Sugg KB, Disser NP, Enselman ERS, Awan TM, Mendias CL. Local
cryotherapy minimally impacts the metabolome and transcriptome of human skeletal
muscle. Sci Rep. 2017 May 25;7(1):2423. doi: 10.1038/s41598-017-02754-5. PMID:
28546635; PMCID: PMC5445066.

33: Saripalli AL, Sugg KB, Mendias CL, Brooks SV, Claflin DR. Active shortening
protects against stretch-induced force deficits in human skeletal muscle. J Appl
Physiol (1985). 2017 May 1;122(5):1218-1226. doi:
10.1152/japplphysiol.01054.2016. Epub 2017 Feb 23. PMID: 28235860; PMCID:
PMC5451535.

34: Werner NL, Alghanem F, Rakestraw SL, Sarver DC, Nicely B, Pietroski RE,
Lange P, Rudich SM, Mendias CL, Rojas-Pena A, Magee JC, Bartlett RH, Ozer K. Ex
Situ Perfusion of Human Limb Allografts for 24 Hours. Transplantation. 2017
Mar;101(3):e68-e74. doi: 10.1097/TP.0000000000001500. PMID: 28222055.

35: Wurtzel CN, Gumucio JP, Grekin JA, Khouri RK Jr, Russell AJ, Bedi A, Mendias
CL. Pharmacological inhibition of myostatin protects against skeletal muscle
atrophy and weakness after anterior cruciate ligament tear. J Orthop Res. 2017
Nov;35(11):2499-2505. doi: 10.1002/jor.23537. Epub 2017 Feb 15. PMID: 28176368;
PMCID: PMC5548641.

36: Sugg KB, Korn MA, Sarver DC, Markworth JF, Mendias CL. Inhibition of
platelet-derived growth factor signaling prevents muscle fiber growth during
skeletal muscle hypertrophy. FEBS Lett. 2017 Mar;591(5):801-809. doi:
10.1002/1873-3468.12571. Epub 2017 Feb 17. PMID: 28129672; PMCID: PMC5352504.

37: Gumucio JP, Flood MD, Bedi A, Kramer HF, Russell AJ, Mendias CL. Inhibition
of prolyl 4-hydroxylase decreases muscle fibrosis following chronic rotator cuff
tear. Bone Joint Res. 2017 Jan;6(1):57-65. doi:
10.1302/2046-3758.61.BJR-2016-0232.R1. PMID: 28108482; PMCID: PMC5301902.

38: Sarver DC, Kharaz YA, Sugg KB, Gumucio JP, Comerford E, Mendias CL. Sex
differences in tendon structure and function. J Orthop Res. 2017
Oct;35(10):2117-2126. doi: 10.1002/jor.23516. Epub 2017 Feb 9. PMID: 28071813;
PMCID: PMC5503813.

39: Dueweke JJ, Awan TM, Mendias CL. Regeneration of Skeletal Muscle After
Eccentric Injury. J Sport Rehabil. 2017 Apr;26(2):171-179. doi:
10.1123/jsr.2016-0107. Epub 2016 Dec 19. PMID: 27992284; PMCID: PMC5393925.

40: Mendias CL, Schwartz AJ, Grekin JA, Gumucio JP, Sugg KB. Changes in muscle
fiber contractility and extracellular matrix production during skeletal muscle
hypertrophy. J Appl Physiol (1985). 2017 Mar 1;122(3):571-579. doi:
10.1152/japplphysiol.00719.2016. Epub 2016 Dec 15. PMID: 27979985; PMCID:
PMC5401954.

41: Garcia SC, Dueweke JJ, Mendias CL. Optimal Joint Positions for Manual
Isometric Muscle Testing. J Sport Rehabil. 2016 Nov 1;25(4):jsr.2015-0118. doi:
10.1123/jsr.2015-0118. Epub 2016 Aug 24. PMID: 27632883; PMCID: PMC5325820.

42: Claflin DR, Roche SM, Gumucio JP, Mendias CL, Brooks SV. Assessment of the
Contractile Properties of Permeabilized Skeletal Muscle Fibers. Methods Mol
Biol. 2016;1460:321-36. doi: 10.1007/978-1-4939-3810-0_22. PMID: 27492182.

43: Hudgens JL, Sugg KB, Grekin JA, Gumucio JP, Bedi A, Mendias CL. Platelet-
Rich Plasma Activates Proinflammatory Signaling Pathways and Induces Oxidative
Stress in Tendon Fibroblasts. Am J Sports Med. 2016 Aug;44(8):1931-40. doi:
10.1177/0363546516637176. Epub 2016 Jul 8. PMID: 27400714; PMCID: PMC4970921.

44: Wilde JM, Gumucio JP, Grekin JA, Sarver DC, Noah AC, Ruehlmann DG, Davis ME,
Bedi A, Mendias CL. Inhibition of p38 mitogen-activated protein kinase signaling
reduces fibrosis and lipid accumulation after rotator cuff repair. J Shoulder
Elbow Surg. 2016 Sep;25(9):1501-8. doi: 10.1016/j.jse.2016.01.035. Epub 2016 Apr
7. PMID: 27068389; PMCID: PMC4992438.

45: Ozer K, Rojas-Pena A, Mendias CL, Bryner BS, Toomasian C, Bartlett RH. The
Effect of Ex Situ Perfusion in a Swine Limb Vascularized Composite Tissue
Allograft on Survival up to 24 Hours. J Hand Surg Am. 2016 Jan;41(1):3-12. doi:
10.1016/j.jhsa.2015.11.003. PMID: 26710728.

46: Gumucio JP, Flood MD, Roche SM, Sugg KB, Momoh AO, Kosnik PE, Bedi A,
Mendias CL. Stromal vascular stem cell treatment decreases muscle fibrosis
following chronic rotator cuff tear. Int Orthop. 2016 Apr;40(4):759-64. doi:
10.1007/s00264-015-2937-x. Epub 2015 Jul 30. PMID: 26224616; PMCID: PMC4733427.

47: Roche SM, Gumucio JP, Brooks SV, Mendias CL, Claflin DR. Measurement of
Maximum Isometric Force Generated by Permeabilized Skeletal Muscle Fibers. J Vis
Exp. 2015 Jun 16;(100):e52695. doi: 10.3791/52695. PMID: 26131687; PMCID:
PMC4545153.

48: Jeffery N, Mendias C. Endocranial and masticatory muscle volumes in
myostatin-deficient mice. R Soc Open Sci. 2014 Dec 17;1(4):140187. doi:
10.1098/rsos.140187. PMID: 26064569; PMCID: PMC4448778.

49: Ozer K, Rojas-Pena A, Mendias CL, Bryner B, Toomasian C, Bartlett RH. Ex
Situ Limb Perfusion System to Extend Vascularized Composite Tissue Allograft
Survival in Swine. Transplantation. 2015 Oct;99(10):2095-101. doi:
10.1097/TP.0000000000000756. PMID: 25929606.

50: Mendias CL, Bakhurin KI, Gumucio JP, Shallal-Ayzin MV, Davis CS, Faulkner
JA. Haploinsufficiency of myostatin protects against aging-related declines in
muscle function and enhances the longevity of mice. Aging Cell. 2015
Aug;14(4):704-6. doi: 10.1111/acel.12339. Epub 2015 Mar 24. PMID: 25808276;
PMCID: PMC4531085.

51: Schwartz AJ, Sarver DC, Sugg KB, Dzierzawski JT, Gumucio JP, Mendias CL. p38
MAPK signaling in postnatal tendon growth and remodeling. PLoS One. 2015 Mar
13;10(3):e0120044. doi: 10.1371/journal.pone.0120044. PMID: 25768932; PMCID:
PMC4359143.

52: Russell KA, Ng R, Faulkner JA, Claflin DR, Mendias CL. Mouse forepaw
lumbrical muscles are resistant to age-related declines in force production. Exp
Gerontol. 2015 May;65:42-5. doi: 10.1016/j.exger.2015.03.003. Epub 2015 Mar 8.
PMID: 25762422; PMCID: PMC4397162.

53: Mendias CL, Lynch EB, Gumucio JP, Flood MD, Rittman DS, Van Pelt DW, Roche
SM, Davis CS. Changes in skeletal muscle and tendon structure and function
following genetic inactivation of myostatin in rats. J Physiol. 2015 Apr
15;593(8):2037-52. doi: 10.1113/jphysiol.2014.287144. Epub 2015 Feb 25. PMID:
25640143; PMCID: PMC4405758.

54: Gumucio JP, Sugg KB, Mendias CL. TGF-β superfamily signaling in muscle and
tendon adaptation to resistance exercise. Exerc Sport Sci Rev. 2015
Apr;43(2):93-9. doi: 10.1249/JES.0000000000000041. PMID: 25607281; PMCID:
PMC4369187.

55: Fry CS, Lee JD, Mula J, Kirby TJ, Jackson JR, Liu F, Yang L, Mendias CL,
Dupont-Versteegden EE, McCarthy JJ, Peterson CA. Inducible depletion of
satellite cells in adult, sedentary mice impairs muscle regenerative capacity
without affecting sarcopenia. Nat Med. 2015 Jan;21(1):76-80. doi:
10.1038/nm.3710. Epub 2014 Dec 15. PMID: 25501907; PMCID: PMC4289085.

56: Gumucio JP, Phan AC, Ruehlmann DG, Noah AC, Mendias CL. Synergist ablation
induces rapid tendon growth through the synthesis of a neotendon matrix. J Appl
Physiol (1985). 2014 Dec 1;117(11):1287-91. doi:
10.1152/japplphysiol.00720.2014. Epub 2014 Oct 2. PMID: 25277742; PMCID:
PMC4254841.

57: Oak NR, Gumucio JP, Flood MD, Saripalli AL, Davis ME, Harning JA, Lynch EB,
Roche SM, Bedi A, Mendias CL. Inhibition of 5-LOX, COX-1, and COX-2 increases
tendon healing and reduces muscle fibrosis and lipid accumulation after rotator
cuff repair. Am J Sports Med. 2014 Dec;42(12):2860-8. doi:
10.1177/0363546514549943. Epub 2014 Sep 22. PMID: 25245131; PMCID: PMC4246014.

58: Davis ME, Korn MA, Gumucio JP, Harning JA, Saripalli AL, Bedi A, Mendias CL.
Simvastatin reduces fibrosis and protects against muscle weakness after massive
rotator cuff tear. J Shoulder Elbow Surg. 2015 Feb;24(2):280-7. doi:
10.1016/j.jse.2014.06.048. Epub 2014 Sep 9. PMID: 25213828; PMCID: PMC4291297.

59: Mendias CL, Roche SM, Harning JA, Davis ME, Lynch EB, Sibilsky Enselman ER,
Jacobson JA, Claflin DR, Calve S, Bedi A. Reduced muscle fiber force production
and disrupted myofibril architecture in patients with chronic rotator cuff
tears. J Shoulder Elbow Surg. 2015 Jan;24(1):111-9. doi:
10.1016/j.jse.2014.06.037. Epub 2014 Sep 3. PMID: 25193488.

60: Gumucio J, Flood M, Harning J, Phan A, Roche S, Lynch E, Bedi A, Mendias C.
T lymphocytes are not required for the development of fatty degeneration after
rotator cuff tear. Bone Joint Res. 2014 Sep;3(9):262-72. doi:
10.1302/2046-3758.39.2000294. PMID: 25185444; PMCID: PMC4220170.

61: Davis ME, Stafford PL, Jergenson MJ, Bedi A, Mendias CL. Muscle fibers are
injured at the time of acute and chronic rotator cuff repair. Clin Orthop Relat
Res. 2015 Jan;473(1):226-32. doi: 10.1007/s11999-014-3860-y. Epub 2014 Aug 12.
PMID: 25113269; PMCID: PMC4390944.

62: Wood LK, Kayupov E, Gumucio JP, Mendias CL, Claflin DR, Brooks SV. Intrinsic
stiffness of extracellular matrix increases with age in skeletal muscles of
mice. J Appl Physiol (1985). 2014 Aug 15;117(4):363-9. doi:
10.1152/japplphysiol.00256.2014. Epub 2014 Jul 3. PMID: 24994884; PMCID:
PMC4137235.

63: Sugg KB, Lubardic J, Gumucio JP, Mendias CL. Changes in macrophage phenotype
and induction of epithelial-to-mesenchymal transition genes following acute
Achilles tenotomy and repair. J Orthop Res. 2014 Jul;32(7):944-51. doi:
10.1002/jor.22624. Epub 2014 Apr 4. PMID: 24700411; PMCID: PMC4086481.

64: Bedi A, Lynch EB, Sibilsky Enselman ER, Davis ME, Dewolf PD, Makki TA, Kelly
BT, Larson CM, Henning PT, Mendias CL. Elevation in circulating biomarkers of
cartilage damage and inflammation in athletes with femoroacetabular impingement.
Am J Sports Med. 2013 Nov;41(11):2585-90. doi: 10.1177/0363546513499308. Epub
2013 Aug 19. PMID: 23959964; PMCID: PMC4048958.

65: Gumucio JP, Korn MA, Saripalli AL, Flood MD, Phan AC, Roche SM, Lynch EB,
Claflin DR, Bedi A, Mendias CL. Aging-associated exacerbation in fatty
degeneration and infiltration after rotator cuff tear. J Shoulder Elbow Surg.
2014 Jan;23(1):99-108. doi: 10.1016/j.jse.2013.04.011. Epub 2013 Jun 20. PMID:
23790676; PMCID: PMC3785561.

66: Gumucio JP, Flood MD, Phan AC, Brooks SV, Mendias CL. Targeted inhibition of
TGF-β results in an initial improvement but long-term deficit in force
production after contraction-induced skeletal muscle injury. J Appl Physiol
(1985). 2013 Aug 15;115(4):539-45. doi: 10.1152/japplphysiol.00374.2013. Epub
2013 Jun 13. PMID: 23766498; PMCID: PMC3742948.

67: Mendias CL, Lynch EB, Davis ME, Sibilsky Enselman ER, Harning JA, Dewolf PD,
Makki TA, Bedi A. Changes in circulating biomarkers of muscle atrophy,
inflammation, and cartilage turnover in patients undergoing anterior cruciate
ligament reconstruction and rehabilitation. Am J Sports Med. 2013
Aug;41(8):1819-26. doi: 10.1177/0363546513490651. Epub 2013 Jun 5. PMID:
23739685; PMCID: PMC4086614.

68: Davis ME, Gumucio JP, Sugg KB, Bedi A, Mendias CL. MMP inhibition as a
potential method to augment the healing of skeletal muscle and tendon
extracellular matrix. J Appl Physiol (1985). 2013 Sep;115(6):884-91. doi:
10.1152/japplphysiol.00137.2013. Epub 2013 May 2. PMID: 23640595; PMCID:
PMC3764625.

69: Davis ME, Stafford PL, Bradley JR, Bedi A, Mendias CL. Improvement in the
Contractility and Muscle Stem Cell Density of the Rotator Cuff Following
Surgical Repair: A Case Report. JBJS Case Connect. 2012 Oct-Dec;2(4):e75. doi:
10.2106/JBJS.CC.L.00023. PMID: 29252371.

70: Gumucio JP, Mendias CL. Atrogin-1, MuRF-1, and sarcopenia. Endocrine. 2013
Feb;43(1):12-21. doi: 10.1007/s12020-012-9751-7. Epub 2012 Jul 20. PMID:
22815045; PMCID: PMC3586538.

71: Calve S, Isaac J, Gumucio JP, Mendias CL. Hyaluronic acid, HAS1, and HAS2
are significantly upregulated during muscle hypertrophy. Am J Physiol Cell
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72: Gumucio JP, Davis ME, Bradley JR, Stafford PL, Schiffman CJ, Lynch EB,
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73: Mendias CL, Gumucio JP, Lynch EB. Mechanical loading and TGF-β change the
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74: Weist MR, Wellington MS, Bermudez JE, Kostrominova TY, Mendias CL, Arruda
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75: Mendias CL, Gumucio JP, Davis ME, Bromley CW, Davis CS, Brooks SV.
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76: Mendias CL, Gumucio JP, Bakhurin KI, Lynch EB, Brooks SV. Physiological
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77: Mendias CL, Kayupov E, Bradley JR, Brooks SV, Claflin DR. Decreased specific
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78: Faulkner JA, Davis CS, Mendias CL, Brooks SV. The aging of elite male
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79: Mendias CL, Bakhurin KI, Faulkner JA. Tendons of myostatin-deficient mice
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80: Mendias CL, Marcin JE, Calerdon DR, Faulkner JA. Contractile properties of
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81: Mendias CL, Tatsumi R, Allen RE. Role of cyclooxygenase-1 and -2 in
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